N-Cyclohexyl-2-oxo-2-phenylacetamide

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2-(2-Chloro­phen­yl)-2-oxo-N-phenyl­acetamide

In the title compound, C(14)H(10)ClNO(2), the dihedral angle between the two rings is 59.4 (2)°. The two carbonyl groups are oriented almost anti-periplanar to each other, with a torsion angle of -160.43 (2)°. In the crystal, mol-ecules are linked into inversion dimers by pairs of N-H⋯O hydrogen bonds.

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N-Cyclo­hexyl-2-oxo-2-phenyl­acetamide

In the title compound, C(14)H(17)NO(2), the two carbonyl groups are oriented with respect to each other with a torsion angle of -129.9 (3)°. The cyclo-hexane ring adopts a chair conformation. In the crystal, mol-ecules are linked by N-H⋯O hydrogen bonds into a chain running along the a axis.

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N-(2-Oxo-2-phenyl­acet­yl)benzamide

In the title compound, C(15)H(11)NO(3), the two essentially planar benzaldehyde groups [maximum deviations = 0.0487 (12) and 0.0205 (10) Å] are inclined at a dihedral angle of 72.64 (6)° with respect to each other. The bridging C-C-N-C torsion angle is 22.58 (18)°. In the crystal, inter-molecular bifurcated acceptor N-H⋯O and C-H⋯O hydrogen bonds link inversion-related mol-ecules into dimers in...

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2-[2-(2-Carb­oxy­phen­yl)hydrazinyl­idene]-3-oxo-N-phenyl­butyramide

In the title compound, C(17)H(15)N(3)O(4), the mol-ecule is in the keto-hydrazone form. Intra-molecular N-H⋯O hydrogen bonds ensure that the mol-ecule is nearly planar (r.m.s. deviation of non-H atoms is 0.098 Å), with the two benzene rings forming a dihedral angle of 10.04 (2)°. In the crystal, inversion dimers are formed via pairs of O-H⋯O hydrogen bonds involving the -CO(2)H groups.

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rac-2-[2-(4-Fluoro­phen­yl)-2-oxo-1-phenyl­eth­yl]-4-methyl-3-oxo-N-phenyl­penta­namide

The title compound, C(26)H(24)FNO(3), is a critical inter-mediate of a selective and competitive inhibitor of the enzyme 3-hy-droxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase. Inter-molecular N-H⋯O hydrogen bonding generates a chain along [give direction] that is the dominant inter-action in the crystal packing. Inter-molecular C-H⋯O inter-actions are also observed.

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ژورنال

عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online

سال: 2012

ISSN: 1600-5368

DOI: 10.1107/s1600536812023549